Philadelphia 76ers 2021-22 NBA Regular Season is scheduled to start with a basketball game against the New Orleans Pelicans Wednesday, October 20, 2021, at Smoothie King Center, New Orleans, LA and end with a game against the Detroit Pistons Sunday, April 10, 2022, at Wells Fargo Center, Philadelphia.
Here is the 76ers NBA basketball game schedule, start time, date, location, TV channel, and current results you need to know.
| Opponent | Time (ET) | Date | Venue | TV |
| Pelicans | 8:00 PM | Wed, Oct 20 | Smoothie King Center | NBC SPORTS PHILADELPHIA |
| Nets | 7:30 PM | Fri, Oct 22 | Wells Fargo Center | ESPN |
| Thunder | 7:00 PM | Sun, Oct 24 | Paycom Center | NBC SPORTS PHILADELPHIA |
| Knicks | 7:30 PM | Tue, Oct 26 | Madison Square Garden | TNT |
| Pistons | 7:00 PM | Thu, Oct 28 | Wells Fargo Center | NBA TV |
| Hawks | 7:30 PM | Sat, Oct 30 | Wells Fargo Center | NBA TV |
| Trail Blazers | 7:00 PM | Mon, Nov 1 | Wells Fargo Center | NBC SPORTS PHILADELPHIA |
| Bulls | 7:00 PM | Wed, Nov 3 | Wells Fargo Center | NBC SPORTS PHILADELPHIA |
| Pistons | 7:00 PM | Thu, Nov 4 | Little Caesars Arena | NBC SPORTS PHILADELPHIA |
| Bulls | 8:00 PM | Sat, Nov 6 | United Center | NBC SPORTS PHILADELPHIA |
| Knicks | 7:00 PM | Mon, Nov 8 | Wells Fargo Center | NBC SPORTS PHILADELPHIA |
| Bucks | 7:30 PM | Tues, Nov 9 | Wells Fargo Center | TNT |
| Raptors | 7:00 PM | Thu, Nov 11 | Wells Fargo Center | NBA TV |